IMGT Repertoire (IG and TR)

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Alignment of alleles: house mouse (Mus musculus) TRAV6-6, TRAV6D-6 and TRAV6N-6

When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.

Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

• Dots indicate gaps according to the IMGT unique numbering.
• Blanks at the 5' and/or 3' end indicate partial sequences.
• Asterisk (*) in the sequence indicate a STOP-CODON.
• Letters in red correspond to amino acids which are polymorphic in the other alleles.
• Colours are according to Color menu for mutations, Color menu for sequence alignments and Color menu for splicing types.
• The nucleotide (s) in bold and colored in purple (splicing frame 1) or green (splicing frame 2) from the DONOR splice site are added at the beginning of the following exon in order to obtain and to complete the first CODON of the DOMAIN or REGION resulting from the splicing site. These first CODONs are in bold and colored in purple (splicing frame 1) or green (splicing frame 2)
• N (Asn, asparagine) of potential N-glycosylation sites (NXS/T, where X is different from P), (N-linked glycosylation) is shown in green

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.

                                                                                                                               
                                               
                                                1   2   3   4   5   6   7   8   8A  9   10  11  12  13  14  15  16  17  18  19 
                                                G   D   S   V   T   Q   T   E       G   Q   V   T   V   S   E   S   K   S   L  
  AC005240   TRAV6-6*01  F   V-REGION gDNA     gga gat tcc gtg act caa aca gaa ... ggc caa gtg acc gtc tca gaa agc aag tcc ctg 

                                                                                                                               
  AE007512   TRAV6-6*01  F   V-REGION gDNA     --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                               
  AE008685   TRAV6-6*01  F   V-REGION gDNA     --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                               
  AC004101   TRAV6D-6*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                               
  AE007512   TRAV6D-6*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                               
  AE008684   TRAV6D-6*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                               
  AC163653   TRAV6N-6*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- ... --- --- --- --t --- --- --- --- --- --- --- 

                                                                                                                               
  AC188458   TRAV6N-6*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- ... --- --- --- --t --- --- --- --- --- --- --- 

                                                                                                                               
  IMGT000082 TRAV6N-6*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- ... --- --- --- --t --- --- --- --- --- --- --- 

                                                                                        K                                      
  U21448     TRAV6-6*02  (F) V-REGION cDNA                                         --a a-- --- --- --t --- --- --- --- --- --- 

                                                                                        P                           E          
  IMGT000082 TRAV6D-6*02 F   V-REGION gDNA     --- --- --- --- --- --- --- --- ... --- -c- --- --- --- --- --- --- g-- --- --- 

                                                                                        P                           E          
  X05187     TRAV6D-6*02 F   V-REGION gDNA     --- --- --- --- --- --- --- --- ... --- -c- --- --- --- --- --- --- g-- --- --- 

                                                                                                                               
  U90513     TRAV6-6*03  (F) V-REGION cDNA         --- --- --- --- --- --- --- ... --- --- --- --t --- --- --- --- --- --- --- 

                                                                                                                               
  M16676     TRAV6D-6*03 (F) V-REGION cDNA     --- --- --- --- --- --- --- --- ... --- --- --- --t --- --- --- --- --- --- --- 

                                                                                        P                           E          
  IMGT000082 TRAV6-6*04  F   V-REGION gDNA     --- --- --- --- --- --- --- --- ... --- -c- --- --- --- --- --- --- g-- --- --- 

                                                                                                        T                      
  U21397     TRAV6D-6*04 (F) V-REGION cDNA                                                 --t --t --t a-- --- --- --- --- --- 

                                                                                                                               
  AY665736   TRAV6D-6*05 (F) V-REGION cDNA     --- --- --- --- --- --- --- --- ... --- --- --- --t --- --- --- --- --- --- --- 

                                                                                                                               
  AY665730   TRAV6D-6*05 (F) V-REGION cDNA     --- --- --- --- --- --- --- --- ... --- --- --- --t --- --- --- --- --- --- --- 



                                                                           ___________________CDR1-IMGT____________________    
                                               
                                                20  21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39 
                                                I   I   N   C   T   Y   S   T   T   S   I                   A   Y   P   N   L  
  AC005240   TRAV6-6*01  F   V-REGION gDNA     ata ata aat tgc acg tat tca acc aca agc ata ... ... ... ... gct tac cct aat ctt 

                                                                                                                               
  AE007512   TRAV6-6*01  F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- --- --- --- --- 

                                                                                                                               
  AE008685   TRAV6-6*01  F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- --- --- --- --- 

                                                                            A                                                  
  AC004101   TRAV6D-6*01 F   V-REGION gDNA     --- --- --- --- --- --- --- g-- --- --- --- ... ... ... ... --- --- --- --- --- 

                                                                            A                                                  
  AE007512   TRAV6D-6*01 F   V-REGION gDNA     --- --- --- --- --- --- --- g-- --- --- --- ... ... ... ... --- --- --- --- --- 

                                                                            A                                                  
  AE008684   TRAV6D-6*01 F   V-REGION gDNA     --- --- --- --- --- --- --- g-- --- --- --- ... ... ... ... --- --- --- --- --- 

                                                                            A                               G                  
  AC163653   TRAV6N-6*01 F   V-REGION gDNA     --- --- --- --- --- --- --- g-- --- --- --- ... ... ... ... -g- --- --- --- --- 

                                                                            A                               G                  
  AC188458   TRAV6N-6*01 F   V-REGION gDNA     --- --- --- --- --- --- --- g-- --- --- --- ... ... ... ... -g- --- --- --- --- 

                                                                            A                               G                  
  IMGT000082 TRAV6N-6*01 F   V-REGION gDNA     --- --- --- --- --- --- --- g-- --- --- --- ... ... ... ... -g- --- --- --- --- 

                                                                                                                               
  U21448     TRAV6-6*02  (F) V-REGION cDNA     --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- --- --- --- --- 

                                                                            A                                                  
  IMGT000082 TRAV6D-6*02 F   V-REGION gDNA     --- --- --- --- --- --- --- g-- --- --- --- ... ... ... ... --- --- --- --- --- 

                                                                            A                                                  
  X05187     TRAV6D-6*02 F   V-REGION gDNA     --- --- --- --- --- --- --- g-- --- --- --- ... ... ... ... --- --- --- --- --- 

                                                                        L                                   G                  
  U90513     TRAV6-6*03  (F) V-REGION cDNA     --- --- --- --- --- --- -t- --- --- --- --- ... ... ... ... -g- --- --- --- --- 

                                                                            A                               G                  
  M16676     TRAV6D-6*03 (F) V-REGION cDNA     --- --- --- --- --- --- --- g-- --- --- --- ... ... ... ... -g- --- --- --- --- 

                                                                            A                                                  
  IMGT000082 TRAV6-6*04  F   V-REGION gDNA     --- --- --- --- --- --- --- g-- --- --- --- ... ... ... ... --- --- --- --- --- 

                                                                            A                               G                  
  U21397     TRAV6D-6*04 (F) V-REGION cDNA     --- --- --- --- --- --- --- g-- --- --- --- ... ... ... ... -g- --- --- --- --- 

                                                                            A                               G                  
  AY665736   TRAV6D-6*05 (F) V-REGION cDNA     --- --- --- --- --t --- --- g-- --- --- --- ... ... ... ... -g- --- --- --- --- 

                                                                            A                               G                  
  AY665730   TRAV6D-6*05 (F) V-REGION cDNA     --- --- --- --- --t --- --- g-- --- --- --- ... ... ... ... -g- --- --- --- --- 



                                                                                                               _______________C
                                               
                                                40  41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59 
                                                F   W   Y   V   R   Y   P   G   E   G   L   Q   L   L   L   K   V   I   T   A  
  AC005240   TRAV6-6*01  F   V-REGION gDNA     ttc tgg tat gtt cga tat cct gga gaa ggt cta caa ctc ctc ctg aaa gtc att acg gct 

                                                                                                                               
  AE007512   TRAV6-6*01  F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                               
  AE008685   TRAV6-6*01  F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                               
  AC004101   TRAV6D-6*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                               
  AE007512   TRAV6D-6*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                               
  AE008684   TRAV6D-6*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                               
  AC163653   TRAV6N-6*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                               
  AC188458   TRAV6N-6*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                               
  IMGT000082 TRAV6N-6*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                               
  U21448     TRAV6-6*02  (F) V-REGION cDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                               
  IMGT000082 TRAV6D-6*02 F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                               
  X05187     TRAV6D-6*02 F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                               
  U90513     TRAV6-6*03  (F) V-REGION cDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                        L               P                                      
  M16676     TRAV6D-6*03 (F) V-REGION cDNA     --- --- --- --- --- --c -t- --- --- --- -cg --- --- --- --- --- --- --- --- --- 

                                                                                                                               
  IMGT000082 TRAV6-6*04  F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                               
  U21397     TRAV6D-6*04 (F) V-REGION cDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                               
  AY665736   TRAV6D-6*05 (F) V-REGION cDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                               
  AY665730   TRAV6D-6*05 (F) V-REGION cDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- 



                                               DR2-IMGT________________                                                        
                                               
                                                60  61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79 
                                                            G   Q   K   G   S   S                       R   G   F   E   A   T  
  AC005240   TRAV6-6*01  F   V-REGION gDNA     ... ... ... ggc cag aag gga agc agc ... ... ... ... ... aga ggg ttt gaa gcc aca 

                                                                                                                               
  AE007512   TRAV6-6*01  F   V-REGION gDNA     ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 

                                                                                                                               
  AE008685   TRAV6-6*01  F   V-REGION gDNA     ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 

                                                                                                                               
  AC004101   TRAV6D-6*01 F   V-REGION gDNA     ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 

                                                                                                                               
  AE007512   TRAV6D-6*01 F   V-REGION gDNA     ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 

                                                                                                                               
  AE008684   TRAV6D-6*01 F   V-REGION gDNA     ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 

                                                                                                                               
  AC163653   TRAV6N-6*01 F   V-REGION gDNA     ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 

                                                                                                                               
  AC188458   TRAV6N-6*01 F   V-REGION gDNA     ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 

                                                                                                                               
  IMGT000082 TRAV6N-6*01 F   V-REGION gDNA     ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 

                                                                                                                               
  U21448     TRAV6-6*02  (F) V-REGION cDNA     ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 

                                                                                                                               
  IMGT000082 TRAV6D-6*02 F   V-REGION gDNA     ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 

                                                                                                                               
  X05187     TRAV6D-6*02 F   V-REGION gDNA     ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 

                                                                                                                               
  U90513     TRAV6-6*03  (F) V-REGION cDNA     ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 

                                                                                                                               
  M16676     TRAV6D-6*03 (F) V-REGION cDNA     ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 

                                                                                                                               
  IMGT000082 TRAV6-6*04  F   V-REGION gDNA     ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 

                                                                                                                               
  U21397     TRAV6D-6*04 (F) V-REGION cDNA     ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 

                                                                                                                               
  AY665736   TRAV6D-6*05 (F) V-REGION cDNA     ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 

                                                                                                                               
  AY665730   TRAV6D-6*05 (F) V-REGION cDNA     ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 



                                                                                                                               
                                               
                                                80  81  82  83  84 84A  85  86  87  88  89  90  91  92  93  94  95  96  97  98 
                                                Y   N   K   E   T       T   S   F   H   L   Q   K   A   S   V   Q   E   S   D  
  AC005240   TRAV6-6*01  F   V-REGION gDNA     tac aat aaa gaa acc ... acc tcc ttc cac ttg cag aaa gcc tca gtg caa gag tca gac 

                                                                                                                               
  AE007512   TRAV6-6*01  F   V-REGION gDNA     --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                               
  AE008685   TRAV6-6*01  F   V-REGION gDNA     --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                               
  AC004101   TRAV6D-6*01 F   V-REGION gDNA     --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                               
  AE007512   TRAV6D-6*01 F   V-REGION gDNA     --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                               
  AE008684   TRAV6D-6*01 F   V-REGION gDNA     --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                A                                                              
  AC163653   TRAV6N-6*01 F   V-REGION gDNA     --- --- --- --- g-- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                A                                                              
  AC188458   TRAV6N-6*01 F   V-REGION gDNA     --- --- --- --- g-- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                A                                                              
  IMGT000082 TRAV6N-6*01 F   V-REGION gDNA     --- --- --- --- g-- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                               
  U21448     TRAV6-6*02  (F) V-REGION cDNA     --- --- --- --- --- ... --g --- --- --- --- --- --- --- --- --- --g --a --- --- 

                                                                                                                               
  IMGT000082 TRAV6D-6*02 F   V-REGION gDNA     --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                               
  X05187     TRAV6D-6*02 F   V-REGION gDNA     --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                        A                                                      
  U90513     TRAV6-6*03  (F) V-REGION cDNA     --- --- --- --- --- ... g-- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                A                                                              
  M16676     TRAV6D-6*03 (F) V-REGION cDNA     --- --- --- --- g-- ... --- --- --- --- --- --- --- --- --- --- --- --- --g --- 

                                                                                                                               
  IMGT000082 TRAV6-6*04  F   V-REGION gDNA     --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                A                                                              
  U21397     TRAV6D-6*04 (F) V-REGION cDNA     --- --- --- --- g-- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                A                                                              
  AY665736   TRAV6D-6*05 (F) V-REGION cDNA     --- --- --- --- g-- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                A                                                              
  AY665730   TRAV6D-6*05 (F) V-REGION cDNA     --- --- --- --- g-- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- 



                                                                       ___CDR3-IMGT____
                                               
                                                99 100 101 102 103 104 105 106 107 
                                                S   A   V   Y   Y   C   A   L   G  
  AC005240   TRAV6-6*01  F   V-REGION gDNA     tcg gct gtg tac tac tgt gct ctg ggt ga

                                                                                   
  AE007512   TRAV6-6*01  F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --

                                                                                   
  AE008685   TRAV6-6*01  F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --

                                                                                S  
  AC004101   TRAV6D-6*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- a-- --

                                                                                S  
  AE007512   TRAV6D-6*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- a-- --

                                                                                S  
  AE008684   TRAV6D-6*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- a-- --

                                                                                S  
  AC163653   TRAV6N-6*01 F   V-REGION gDNA     --- --- --- --- --- --c --- --- a-- --

                                                                                S  
  AC188458   TRAV6N-6*01 F   V-REGION gDNA     --- --- --- --- --- --c --- --- a-- --

                                                                                S  
  IMGT000082 TRAV6N-6*01 F   V-REGION gDNA     --- --- --- --- --- --c --- --- a-- --

                                                                                   
  U21448     TRAV6-6*02  (F) V-REGION cDNA     --- --- --- --- --- --- --- --- --- 

                                                                                   
  IMGT000082 TRAV6D-6*02 F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --

                                                                                   
  X05187     TRAV6D-6*02 F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --

                                                                                   
  U90513     TRAV6-6*03  (F) V-REGION cDNA     --- --- --- --- --- --c --- --- --- 

                                                                               
  M16676     TRAV6D-6*03 (F) V-REGION cDNA     --- --- --- --- --- --c --- --- a-

                                                                                   
  IMGT000082 TRAV6-6*04  F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --

                                                                               
  U21397     TRAV6D-6*04 (F) V-REGION cDNA     --- --- --- --- --- --c --- --- a

                                                                                S  
  AY665736   TRAV6D-6*05 (F) V-REGION cDNA     --- --- --- --- --- --c --- --- a-- --

                                                                               
  AY665730   TRAV6D-6*05 (F) V-REGION cDNA     --- --- --- --- --- --c --- --- a-

This alignment of allele is generated by IMGT/OutilAllele (Mehdi Yousfi, Chantal Ginestoux, Perrine Pégorier and Patrice Duroux).

Created:

05/09/2022

Last updated:

22/09/2023

Authors:

Guilhem Zeitoun